One-pot Multi-component Synthesis of Some Pharmacologically Significant 2,4,5-Tri and 1,2,4,5-Tetrasubstituted Imidazoles: A Review

Bansal, Ravi and Soni, Pradeep K. and Ahirwar, Mukesh K. and Halve, Anand K. (2016) One-pot Multi-component Synthesis of Some Pharmacologically Significant 2,4,5-Tri and 1,2,4,5-Tetrasubstituted Imidazoles: A Review. International Research Journal of Pure and Applied Chemistry, 11 (4). pp. 1-26. ISSN 22313443

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Abstract

Heterocyclic compounds are acquiring more importance in recent years because of their pharmacological activities. Compounds containing imidazole moiety have many pharmacological properties and play important role in biochemical processes. Imidazole is a natural compound which exists in many important natural molecules such as the amino acid histidine, vitamin B12, histamine, biotin and purines like adenine and guanine. Imidazole derivatives play significant roles in various pharmacological activities such as anticancer, antibacterial, antifungal, antiviral, anti-HIV and antitubercular. This article aims to review the work in the methods of synthesis using various catalytic system, solvent condition and pharmacological potential of 2,4,5-tri and 1,2,4,5-tetrasubstituted imidazoles reported during last 15 years.

Item Type: Article
Subjects: Research Asian Plos > Chemical Science
Depositing User: Unnamed user with email support@research.asianplos.com
Date Deposited: 19 Jun 2023 11:30
Last Modified: 28 Oct 2024 08:21
URI: http://abstract.stmdigitallibrary.com/id/eprint/871

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