Lin, Xiaoting and Qi, Guoyan (2022) Observation on the efficacy of different methylprednisolone regimens in the treatment of myasthenia gravis. Pakistan Journal of Medical Sciences, 38 (4). ISSN 1682-024X
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Abstract
Objective: To investigate the efficacy of different methylprednisolone regimens in the treatment of myasthenia gravis (MG).
Methods: A total of 98 patients with MG admitted to Shijiazhuang People’s Hospital from December 2018 to November 2019 were randomly divided into two groups, with 49 cases in each group. Patients in the control group received high-dose methylprednisolone pulse therapy, while those in the experimental group received medium-dose periodic therapy of methylprednisolone. Anti-acetylcholine receptor antibodies (AChRab), clinical absolute scores, complement levels (C3, C4), T lymphocyte subsets (CD3+, CD4+, CD4+CD25+), cytokines [interferon-γ (INF-γ), transforming growth factor-β1 (TGF-β1), interleukin-6 (IL- 6), interleukin-18 (IL-18)], and changes in quality of life [15-item Myasthenia Gravis Quality of Life Scale (MGQOL-15) score] were compared between the two groups before
Item Type: | Article |
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Subjects: | Research Asian Plos > Medical Science |
Depositing User: | Unnamed user with email support@research.asianplos.com |
Date Deposited: | 12 Apr 2023 08:10 |
Last Modified: | 19 Oct 2024 11:40 |
URI: | http://abstract.stmdigitallibrary.com/id/eprint/479 |