Klipple Trenaunay Syndrome-A Rare Disorder with Multisystemic Clinical Attributes: Yet Exploring Options to Treat

This chapter discuss about a case diagnosed with Klippel Trenaunay syndrome, presenting with capillary malformation, venous malformation, bone or soft-tissue growth, and relevant complications.

A rare condition known as Klippel-Trenaunay syndrome is characterized by aberrant development of the lymphatic system, blood vessels, soft tissues, and blood vessels. The main characteristics included bony and tissue hypergrowth, vein deformity, and port wine stain resembling a birthmark, either with or without lymphatic anomalies. We report a patient of 19-years old male eventually diagnosed with Klipple-Trenaunay syndrome (KTS) who presented initially with swelling of his feet, skin erosion, and bloody discharge. Associated findings were bluish skin discoloration, nodularity, and bleeding per rectum. The patient was found to have anemia and heart failure. Colonoscopy/Sigmoidoscopy showed vascular malformation and an active bleeding site. We present a case of KTS manifesting most of the clinical attributes with an interesting clinical course of arteriovenous malformation, soft tissue, capillary, lymphatic, and vascular malformation. This case needs further assistance in genetic analysis with more evaluation to learn genetic mutation, management, and future treatment plan to improve patient quality of life like this similar condition.